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ambr® crossflow

The High Throughput Solution for Parallel Screening

 

 

  • Study factors for manufacturability
  • Up to 16 automated, parallel trials
  • Lowest process volumes – 5 mL recirculation volume
 

ambr® crossflow provides at early development stages access to molecule behavior related to viscosity, buffer composition, shear stress and performance in membrane processes. It enables a lot of important additional decision criteria for the final candidate selection and speeds up this process significantly.

A small scale, high throughput automated system enables greater number of molecule | buffer combinations and process control  conditions to be investigated. As a result early stage R&D productivity and efficiency will be improved significantly while costs per  experiment are reduced.

ambr® crossflow is a benchtop crossflow system optimised for ultrafiltration and diafiltration applications. It is a small scale screening system with a minimum recirculation volume of 5 mL and a dedicated new range of ambr® CF filter cassettes with 10 cm² membrane area. Parallel operation is achieved with 4 independent crossflow channels per module, with up to 4 modules managed by one control station. This means ambr® crossflow is capable of performing membrane screenings with up to 16 ambr® CF filters simultaneously.

Intuitive hardware and software design ensures that the system is quick to set up and easy to use, while full system automation ensures reliable process control and reduced manual intervention.

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ambr® crossflow 4- to 16-channel module with system controller

Flexibility for Automated Processing

Expand your ambr® crossflow system and tailor it to your actual demand with 4, 8, 12 or 16 channels.

Each ambr® crossflow module consists of four independent crossflow channels, and up to 4 modules can be managed by one control station. This enables you to perform membrane screening with up to 16 ambr® CF filters and 32 diafiltration buffers.

Increase R&D Productivity

ambr® crossflow can be used as a ranking tool, to optimise, for example:

  • process conditions, e.g. TMP or flowrate
  • processing conditions, e.g. buffer type or volumes required
  • pH and | or conductivity values

ambr® crossflow Overview

For more information please click on the

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Intuitive Control Software

Smart Scalability

Crossflow Solutions from Early to Late Process Development

Linear scale up from 50 cm² to as much as 0.14 m² on SARTOFLOW® Smart and from 0.1m² to 2.1 m² on SARTOFLOW® Advanced at lowest recirculation volumes. Two systems that offer a combination of full flexibility and outstanding crossflow filtration performance.

Learn more about SARTOFLOW Systems

Are you interested in speeding up the development process with this high throughput technology?

Please contact us.

 

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