Meet Kate, an induced pluripotent stem cell, or iPSC therapy researcher and developer.
She is focused on developing a differentiation
protocol for a therapeutic iPSC-derived cell and
on defining critical quality attributes, or CQAs.
However, Kate’s iPSC research may run into
delays with time-to-market, and she may face difficulties
translating characterization to insights.
This is often due to low throughput,
and a lack of cell characterization insights.
Thankfully, Sartorius PSC Functional and
Phenotypic Characterization Solution helps Kate’s R&D group
deliver the CQAs that their Process Development group needs.
Let’s learn more!
The Solution aids Kate and her team by controlling variability.
It ensures reproducibility of Kate’s experiments with
consistent, xeno-free, serum-free growth medium,
high-recovery cryopreservation medium,
precise pipetting tools,
and contamination checks.
The Solution enables automation and throughput when developing protocols and
performing phenotypic and functional characterization of iPSCs.
It enables the analysis of cells in 96 and 384 well plates and systematic
validation of findings with 24-48 sample miniaturized assay platform.
At the same time, Kate obtains a comprehensive understanding of iPSCs
throughout the differentiation protocol thanks to
continuous live-cell analysis and multiplex phenotyping.
With the Sartorius Solution,
Kate is equipped with the information she needs in order to develop and
optimize differentiation protocols for her iPSC derivative and
to identify the CQAs to enable process development.