Polishing in Viral Vector Vaccine Process

Sartorius offers solutions for contaminant removal that are designed to deliver better results in less time, from development to manufacturing scale. Our team works with you to co-develop solutions to get to market faster.

Polishing at a Glance

Solutions for Process Development

Sartobind® membrane adsorbers are chromatographic membranes utilized to efficiently remove contaminants such as DNA and host cell proteins.

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Solutions at Pilot & Manufacturing Scale

Sartobind® membrane technology allows you to shift from slow and oversized expensive columns to small, single-use capsules. You can save up to...

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Process Development of the Polishing Step by Membrane Chromatography

Sartobind® membrane adsorbers are chromatographic membranes utilized to efficiently remove contaminants such as DNA and host cell proteins. Sartobind® offers a number of benefits compared to conventional column chromatography such as easy handling, high flow and high capacities for large molecules. Sartobind® ligands can be evaluated in small scalable format (96 well plates, Sartobind® Pico, Sartobind Nano®) for process development. You can use our MODDE® Design of Experiments software solutions to achieve outstanding results in no time.

Sartobind® Q

A strong anion exchanger for purification of viruses such as adenoviruses or lentiviruses

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Sartobind STIC®

A salt-tolerant anion exchanger for DNA and host cell proteins removal

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MODDE®

A Design of Experiments software solution enabling effective experimentation, identification of (Critical) Process Parameters and set-up of a...

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Polishing at Pilot and Manufacturing Scale

Sartobind® membrane technology allows you to shift from slow and oversized expensive columns to small, single-use capsules. You can save up to 70% processing time and work space with ready-to-use membrane chromatography. The design of Sartobind® capsule, features optimized flow channels, significantly reducing void volume, sharpening breakthrough curves and reducing elution volumes. And as viral vector processes grow in size, a range of new cassette format accommodates the necessary process scale. Contained capsules and sterile gamma irradiated cassettes enable purification of viral vectors that cannot be sterile filtered.

Sartobind® Cassettes

A new modular format for purification of viral vectors at large scale

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Flexsafe® 2D和3D工艺袋

全新的一次性技术标杆产品,Flexsafe 工艺袋能够保障供应,具有出色的生物相容性、纯度和稳健性,兼具安全方便的储存和运输特性

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Connectors | Disconnectors

A wide range of process transfer systems & connectors for fast and reliable sterile connections | disconnections and sterile fluid transfer

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SIMCA®

A Multivariate Data Analysis software solution to analyze and visualize complex data to build process understanding

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Go Now to the Next Steps of the Viral Vectors Process

Step 7: Capture

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Step 9: Buffer Exchange

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了解我们对病毒载体的质量控制和测试要求

监管合规性质量控制和测试

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能够实现病毒定量的病毒计数器

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生物安全测试服务

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